Ìåòà. Îö³íèòè îñîáëèâîñò³ ðîçâèòêó àðòåð³àëüíî¿ ã³ïåðòåí糿 ó ëþäåé íà òë³ ìåòàáîë³÷íîãî ñèíäðîìó òà îá´ðóíòóâàòè ïðèíöèïè õàð÷óâàííÿ, ùîäî ïðîô³ëàêòèêè.
Îá'ºêò ³ ìåòîäè äîñë³äæåííÿ. Áóëè îáñòåæåí³ 432 äîðîñëèõ ïàö³ºíò³â â³êî â³ä 20 äî 69 ðîê³â, ñåðåä íèõ 349 æ³íîê ³ 83 ÷îëîâ³êè. Îïèòóâàííÿ ïðîâîäèëîñÿ ñåðåä ðåñïîíäåíò³â çà äîïîìîãîþ àíêåòóâàííÿ. Ô³êñóâàëèñÿ çàãàëüíî êë³í³÷í³ ïîêàçíèêè: âèçíà÷åííÿ çðîñòó, âàãè ç íàñòóïíèì ðîçðàõóíêîì ³íäåêñó ìàñè ò³ëà (êã/ì2), ñèñòîë³÷íîãî (ÑÀÒ) òà ä³àñòîë³÷íîãî (ÄÀÒ) àðòåð³àëüíîãî òèñêó. Ñåðåä ëàáîðàòîðíèõ ïîêàçíèê³â ïðèâåðíóëè óâàãó íàñòóïí³: çàãàëüíèé õîëåñòåðèí(Çàã Õñ), ãëþêîçà, ìàðêåð ³íñóë³íîðåçèñòåíòíîñò³ (³íäåêñ Homa-IR). Ñòàòèñòè÷íà îáðîáêà ïðîâîäèëàñÿ çà äîïîìîãîþ êîðåëÿö³éíîãî àíàë³çó. Òåìà ñòàòò³ âèñâ³òëåíà â ãðàô³êàõ, òàáëèöÿõ òà ä³àãðàìàõ.
ϳä ÷àñ äîñë³äæåííÿ áóëè äîòðèìàí³ ïðèíöèïè á³îåòèêè, à òàêîæ ïîëîæåííÿ Íàêàçó ̳í³ñòåðñòâà îõîðîíè çäîðîâ’ÿ «Ïðî çàòâåðäæåííÿ ïîðÿäêó ïðîâåäåííÿ êë³í³÷íèõ âèïðîáîâóâàíü» ³ Òèïîâîãî ïîëîæåííÿ ïðî êîì³ñ³þ ç ïèòàíü åòèêè ¹66 â³ä 13.02.2006. Óñ³ ïàö³ºíòè ï³äïèñàëè ³íôîðìîâàíó çãîäó íà ó÷àñòü â îáñòåæåí³.
Ðåçóëüòàòè äîñë³äæåííÿ òà ¿õ îáãîâîðåííÿ. Ñòâîðåíî ðåºñòð ðåñïîíäåíò³â – äîðîñëèõ ÷îëîâ³ê³â òà æ³íîê, ÿê³ îïèíèëèñÿ ï³ä âïëèâîì ìîäèô³êîâàíîãî ÷èííèêà – íàäì³ðíî¿ âàãè ÷è îæèð³ííÿ, ùî º òðèãåðîì ïîøèðåíîñò³ òàêèõ ñòàí³â, ÿê àðòåð³àëüíà ã³ïåðòåíç³ÿ, ã³ïåðõîëåñòåðèíåì³ÿ, ã³ïåðãë³êåì³ÿ. Äîñë³äæåííÿ âñòàíîâèëî, ùî 85% ðåñïîíäåíò³â ìàëè ð³çí³ ñòóïåí³ îæèð³ííÿ ÷è íàäì³ðíó âàãó. Òàêîæ áóëî ï³äòâåðäæåíî äîñòîâ³ðíèé çâ'ÿçîê ì³æ ê³ëüê³ñíèìè ïîêàçíèêàìè çà äîïîìîãîþ êîðåëÿö³éíîãî àíàë³çó ϳðñîíà (r) ì³æ ïàðàìåòðàìè ÑÀÒ ³ ÄÀÒ (r=0,9608, ð≤0,01), ²ÌÒ (r=0,75664, ð≤0,05), Çàã Õñ (r=0,69983, ð≤0,05), ãëþêîçîþ (r=0,73268, ð≤0,05); ì³æ ²ÌÒ ³ Çàã Õñ (r=0,7139, ð≤0,05), ³ ãëþêîçîþ (r=0,63816, ð≤0,05). Öå ùå ðàç ï³äòâåðäæóº, ùî ÑÀÒ çá³ëüøóºòüñÿ îäíîìîìåíòíî ç ÄÀÒ, òèñê çàëåæèòü â³ä çá³ëüøåííÿ ð³âíÿ ãëþêîçè, õîëåñòåðèíó, ²ÌÒ òîìó, ùî ö³ ïàðàìåòðè âïëèâàþòü íà ñòàí ñóäèí ³ ñåðöÿ.
Âèñíîâêè. Ïîãëèáëåíå, êîìïëåêñíå îáñòåæåííÿ ç îäíî÷àñíèì âèçíà÷åííÿì àíòðîïîìåòðè÷íèõ, ãåìîäèíàì³÷íèõ, ãîðìîíàëüíèõ ïîêàçíèê³â ñòàíó çäîðîâ’ÿ äîçâîëèëî îá´ðóíòóâàòè ðîëü õàð÷óâàííÿ ó ïðîô³ëàêòèö³ àðòåð³àëüíî¿ ã³ïåðòåí糿 ó õâîðèõ ç ìåòàáîë³÷íèì ñèíäðîìîì. Ïîêàçàíî, ùî 85% ðåñïîíäåíò³â ìàëè ð³çí³ ñòóïåí³ îæèð³ííÿ ÷è íàäì³ðíó âàãó, ùî ìîæíà ðîçö³íþâàòè ÿê ôàêòîð ðèçèêó ðîçâèòêó àðòåð³àëüíî¿ ã³ïåðòåí糿. Âñòàíîâëåíî äîñòîâ³ðíèé çâ’ÿçîê ì³æ ê³ëüê³ñíèìè ïîêàçíèêàìè çà äîïîìîãîþ êîðåëÿö³éíîãî àíàë³çó ϳðñîíà (r) ì³æ òèñêîì ³ çàãàëüíèì õîëåñòåðèíîì, ãëþêîçîþ, ³íäåêñîì ìàñè ò³ëà. Âèñâ³òëåíî, ùî ðàö³îíàëüí³ çì³íè â õàð÷îâèõ çâè÷êàõ – öå ïðîñòèé, äîñòóïíèé ³ åôåêòèâíèé øëÿõ äî çäîðîâîãî ñåðöÿ òà äîâãîë³òòÿ.
Ïðîô³ëàêòè÷í³ ä³¿. Ç ìåòîþ ïðîô³ëàêòèêè âèíèêíåííÿ àðòåð³àëüíî¿ ã³ïåðòåí糿 ïðîïîíóºòüñÿ âïðîâàäèòè ÷îëîâ³êàì ³ æ³íêàì ïðèíöèïè õàð÷óâàííÿ.

Àðòåð³àëüíà ã³ïåðòåíç³ÿ, ìåòàáîë³÷íèé ñèíäðîì, ³íäåêñ ìàñè ò³ëà, àðòåð³àëüíèé òèñê, õàð÷óâàííÿ.

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