Âïðîâàäæåííÿ òà ïîøóê íîâèõ õ³ì³÷íèõ ìàòåð³àë³â (ïîë³ìåðíèõ ñèíòåòè÷íèõ ìàòåð³àë³â, ÏÑÌ) òà ïðåïàðàò³â ïîáóòîâî¿ õ³ì³¿ (ÏÁÕ) â æèòòÿ ñóñï³ëüñòâà ðîçïî÷àëîñü á³ëüø í³æ 100 ðîê³â òîìó ç ñèíòåçó ôåíîëôîðìàëüäåã³äíî¿ ñìîëè òà àöèëàì³íîåòèëòðèëê³ëàììîí³ºâî¿ ñîë³ é íå çàâåðøóºòüñÿ ñüîãîäí³. Ïîðÿä ç ö³ííèìè åêñïëóàòàö³éíèìè âëàñòèâîñòÿìè ö³ ìàòåð³àëè íåñóòü ïîòåíö³éíó íåáåçïåêó çäîðîâ’þ íàñåëåííþ, ÿêà ìîæå ïðîÿâëÿòèñü ó âèãëÿä³ àëåðã³é, çíèæåíí³ ³ìóí³òåòó òà ³íøèõ íåñïðèÿòëèâèõ ïðîÿâàõ. Ó çâ’ÿçêó ç öèì, ö³ ìàòåð³àëè ñòàëè îá’ºêòîì äîñë³äæåíü çà íàïðÿìêîì – «ã³ã³ºíà ïîë³ìåð³â òà ïðåïàðàò³â ïîáóòîâî¿ õ³ì³¿».
Ìåòà ðîáîòè: ïðîàíàë³çóâàòè ðåçóëüòàòè íàóêîâèõ äîñë³äæåíü çà íàïðÿìêîì «ã³ã³ºíà ïîë³ìåð³â òà ïðåïàðàò³â ïîáóòîâî¿ õ³ì³¿» ç ìîìåíòó ñòàíîâëåííÿ ëàáîðàòî𳿠áåçïåêè õ³ì³÷íèõ ìàòåð³àë³â ÄÓ «²íñòèòóò ãðîìàäñüêîãî çäîðîâ’ÿ ³ì. Î.Ì. Ìàð纺âà Íàö³îíàëüíî¿ àêàäå쳿 ìåäè÷íèõ íàóê Óêðà¿íè».
Ðåçóëüòàòè àíàë³çó. Âñòàíîâëåíà á³îëîã³÷íà ä³ÿ ñèíòåòè÷íèõ ìèþ÷èõ çàñîá³â (ÑÌÑ) ³ ïîâåðõíåâî-àêòèâíèõ ðå÷îâèí (ÏÀÐ) ïðè íàøê³ðí³é 䳿 òà îá´ðóíòîâàí³ çàëåæíîñò³ «äîçà-åôåêò».
Ðîçðîáëåí³ ìåòîäè âèçíà÷åííÿ àí³îííèõ (ÏÀÐ). Âñòàíîâëåí³ çàêîíîì³ðíîñò³ ¿õ íàêîïè÷åííÿ â ð³çíèõ îá’ºêòàõ (øê³ðà, ñèðîâàòêà êðîâ³, ñ³ëüñüêîãîñïîäàðñüê³ êóëüòóðè, ´ðóíòè, òêàíèíè).
Ïðîâåäåíà òîêñèêîëîã³÷íà îö³íêà ïðîäóêò³â ãîð³ííÿ ñó÷àñíèõ áóä³âåëüíèõ ³ ëàêîôàðáîâèõ ìàòåð³àë³â ³ ¿õ êîìá³íàö³é òà îá´ðóíòîâàí³ áåçïå÷í³ ð³âí³ ¿õ íàñè÷åíîñò³ â æèòë³.
Äîñë³äæåí³ îñîáëèâîñò³ õ³ì³÷íîãî çàáðóäíåííÿ æèòëà ³ âñòàíîâëåí³ ÷èííèêè, ùî âïëèâàþòü íà éîãî ôîðìóâàííÿ (íàñè÷åí³ñòü ïîë³ìåðíèìè ìàòåð³àëàìè, ïàðàìåòðè ì³êðîêë³ìàòó).
Çà ðåçóëüòàòàìè âèâ÷åííÿ òîêñèêîê³íåòèêè õ³ì³÷íèõ ñïîëóê âñòàíîâëåíî, ùî õðîí³÷íå îòðóºííÿ îðãàí³çìó ï³ä ÷àñ ïîæåæ îáóìîâëåíå òðèâàëîþ çàòðèìêîþ ¿õíüîãî âèâåäåííÿ ç îðãàí³çìó òà ïîðóøåííÿì ìåòàáîë³çìó êèñíþ.
Çà ðåçóëüòàòàìè á³îìîí³òîðèíãó ìåòàë³â âñòàíîâëåíî, ùî êîíöåíòðàö³ÿ ó á³îëîã³÷íèõ ìàòåð³àëàõ ìåòàë³â «òîêñè÷íî¿ ãðóïè» (ñâèíåöü ³ í³êåëü) ç íàðîñòàííÿì â³êó ëþäåé äî 50 ðîê³â íîñèòü ³íòåíñèâíèé õàðàêòåð íàêîïè÷åííÿ, à êîíöåíòðàö³ÿ ìåòàë³â «åñåíö³àëüíî¿ ãðóïè» (ì³äü, öèíê, êîáàëüò, õðîì òà ìàðãàíåöü) ç â³êîì çíèæóºòüñÿ.
Ðîçðîáëåíî ìåòîäè âèçíà÷åííÿ ëåòêèõ õ³ì³÷íèõ ñïîëóê, ì³ãðóþ÷èõ ç ïîë³ìåðíèõ ìàòåð³àë³â òà ê³íåòè÷íà ìîäåëü ïðîãíîçóâàííÿ ¿õí³õ ð³âí³â ó ïîâ³òðÿ ïðèì³ùåíü.

Ïîë³ìåðí³ ìàòåð³àëè, ìèþ÷³ çàñîáè, õ³ì³÷í³ ÷èííèêè ãîð³ííÿ ïîë³ìåð³â, á³îìîí³òîðèíã ìåòàë³â.

1. Chekal VN. [To the question of application of polymeric materials in building]. In: Hygiene of populated places: Scientific conference materials. Kyiv: KNIOKG. 1969:131-2. Russian.

2. Voloshchenko ÎI, Kuzmina AI, Medyanik IA. [Hygienic features of household detergents based on cationic surfactants]. In: Hygiene of populated places. Kyiv: Zdorovye. 1979;18:113-6. Russian.

3. Voloshchenko ÎI. [Ways to improve methodological approaches to the hygienic study of synthetic detergents]. In: [Collection of works on household chemicals]. Moscow: NIITEKHIM;1975:3:18-20. Russian.

4. Chekal VN, Voloshchenko OI, Medyanik IA, Kuzmina AI, Voinova TN, Starikova LA. [Hygienic characteristics of some household chemicals and methodological approaches to their study]. In: Hygiene of populated places: Abstracts of reports of the Scientific Conference. Kyiv: Ministry of Health of the Ukrainian SSR, KNIIOKG; 1971:140-2. Russian.

5. Voloshchenko OI, Medianyk IA. [Chemistry in everyday life and the environment]. Kyiv: Society of Knowledge of the Ukrainian SSR;1978. 206 p. Ukrainian.

6. Lyashenko VI. [Features of gas chromatographic determination of terephthalic acid in atmospheric air]. Hygiene and Sanitation. 1984;7:48-9. Russian.

7. Lyashenko VI, Chekal VN, Makarenko EM. [On methods for determining formaldehyde in air]. Hygiene and Sanitation. 1989;9:42-4. Russian.

8. Lyashenko VI, Rusakova LN, Chekal VN. [Comparative capillary chromatography and its capabilities in the analysis of polluted air]. Hygiene and Sanitation. 1990;1:74-6. Russian.

9. Lyashenko VI, Chekal VN, et al. [Flash desorption is an alternative to existing methods for extracting organic microimpurities from sorbents during gas chromatographic analysis of polluted air]. Hygiene and Sanitation. 1991;4:78-9. Russian.

10. Lyashenko VI. [Gas chromatographic method for the determination of C1-C4 alkyl thiols in the atmosphere]. Journal of Chromatographic Partnership. 2002;1(2):8-11. Ukrainian.

11. Chekal VN. [Hygienic principles for regulating the use of polymer materials in construction]. Abstract of the dissertation of a doctor of medical sciences: 14.00.07. Kiev; 1980. 34 p. Russian.

12. Chekal VN, Voloshchenko OI, Mudryy IV. [Methodological recommendations for the hygienic assessment of clothing and footwear made of polymeric materials]. Moscow; 1987. Russian.

13. Chekal VN. [On the peculiarities of migration of volatile components from shoe products]. Hygiene and Sanitation. 1986;1:64-5. Russian.

14. Bardov VG, Lyashenko VI, et al. [Composition of volatile components released into the environment during the production of epoxy press materials]. In: Materials of the XI scientific and practical conference of the research sector of the A.A. Bogomolets Ukrainian State Medical University. Kyiv; 1993:47-9. Russian.

15. Chekal VM., Voloshchenko OI, Liashenko VI, Raietska OV, Holenkova LG, Holichenkov AM, Maistrenko ZYu, Hladka SA. [Sanitary and hygienic properties of polyvinyl chloride materials and prospects for their further use in household and national economy]. Hygiene of Populated Places. 2000:179-83. Ukrainian.

16. [Prediction of sanitary-chemical properties of polymer materials]. Hygiene and Sanitation. 1985;1:21-3. Russian.

17. Chekal VN, Lyashenko VI. [Methodology for predicting the sanitary and chemical properties of polymer building materials]. Hygiene and Sanitation. 1985;11:38-9. Russian.

18. Chekal VN, Lyashenko VI. [To assess the sanitary and chemical properties of some paints and varnishes used in residential construction]. Hygiene and Sanitation. 1985;11:62-3. Russian.

19. Lyashenko VI, Golichenkov OM, Voloshchenko OI. [Polymer building materials as a dangerous chemical factor in the human environment under fire conditions]. Hygiene of Populated Places. 2012;59:138-45. Ukrainian.

20. Lyashenko VI, Polka NS, et al. [On the issue of studying the health status of children living in conditions of increased background radiation, taking into account the influence of factors in the residential environment of preschool institutions “Chernobyl and human health”]. In: Abstracts of reports of the scientific and practical conference on April 20-22. Part 1. Kyiv; 1993:108-9. Russian.

21. Voloshchenko OI. [Hygienic significance of the functional state of the skin when exposed to synthetic detergents (SMC)]. In: A Magyar - Higienikusok ta rsasaga: III. Nemzeti Kongresszusan (Pecs, 1980, augusztus 26 – 29). Pesz; 1980:299. Russian.

22. Voloshchenko OI, Chekal VN, Medyanik IA. [Hygienic requirements for SMS. In: Surfactants and SMS (ref. information No. 5). Moscow: NIITEKHIM;1972:152-5. Russian.

23. Voloshchenko OI, Medyanik IA, Kuzmina AI. [The influence of some personal hygiene products on the body of animals and humans]. Industry of Household Chemical Goods. 1978;1:22. Russian.

24. Voloshchenko OI, Lyashenko VI, Chekal VN, Golichenkov OM, Raitska OV, Golenkova LG. [Biomonitoring of metals in the bodies of children living in controlled regions of Ukraine “Chernobyl and human health”]. In: Abstracts of reports of the scientific and practical conference on April 20-22. Part 1. Kyiv;1993:68-9. Russian.

25. Liashenko VI, Holichenkov OM, Voloshchenko OI, Chekal VM. [Toxic-kinetic features of the behavior of organochlorine compounds - combustion products of modern polymeric building materials]. Hygiene of Populated Places. 2012;60:159-64. Ukrainian.

26. Liashenko VI. [The role of reactive oxygen species in shaping the development of negative events in the body against the background of xenobiotic metabolism]. Hygiene of Populated Places. 2003:151-6. Ukrainian.

27. Shafran LM, Liashenko VI, Dyshinevich NE, et al. [Determination and hygienic evaluation of the toxicity indicators of the combustion products of polymeric materials. Methodical instructions. MV 8.8.2.4-127-2006 of the Ministry of Health of Ukraine]. Odesa; 2006. Ukrainian.

Ãîë³÷åíêîâ Î.Ì., Ëÿøåíêî Â.²., Ìàéñòðåíêî Ç.Þ., Êó÷åðåíêî Î.Þ. Ñòàíîâëåííÿ òà ðîçâèòîê äîñë³äæåíü ç áåçïåêè õ³ì³÷íèõ ìàòåð³àë³â òà ïðåïàðàò³â ïîáóòîâî¿ õ³ì³¿ â ÄÓ «²íñòèòóò ãðîìàäñüêîãî çäîðîâ’ÿ ³ì. Î.Ì. Ìàð纺âà ÍÀÌÍ Óêðà¿íè». ó㳺íà íàñåëåíèõ ì³ñöü : çá. íàóê. ïð. Ê., 2023. Âèï. 73. Ñ. 68-73.