| ó㳺íà íàñåëåíèõ ì³ñöü | ISSN: 2707-0441 eISSN: 2707-045X |
Âèïóñê 72, 2022 - Ñòîð³íêè: 124-135
Á²ÎËÎò×ÍÎ ÀÊÒÈÂͲ ÑÏÎËÓÊÈ Ë²ÊÀÐÑÜÊÈÕ ÐÎÑËÈÍ – ßÊ ÁÀÇÎÂÀ ÑÊËÀÄÎÂÀ ÕÀÐ×ÎÂÈÕ ÄÎÁÀÂÎÊ. ÍÀÓÊÎÂÈÉ ÀÍÀ˲Ç
Ëÿøåíêî Â.².1, Ãîë³÷åíêîâ Î.Ì.1, Îñòàí³íà Í.Â.1, Êóçíåöîâà Î.Ì.1, Ëåâ³í Ì.Ã.1, Áðÿçêàëî Â.Â.1, Ìàéñòðåíêî Ç.Þ.1
1 ÄÓ "²ÍÑÒÈÒÓÒ ÃÐÎÌÀÄÑÜÊÎÃÎ ÇÄÎÐÎÂ'ß ²Ì. Î.Ì. ÌÀÐǪªÂÀ ÍÀÌÍÓ"
ÀÍÎÒÀÖ²ß:
Äåðæàâíà ïîë³òèêà Óêðà¿íè ó ñôåð³ çàáåçïå÷åííÿ íàñåëåííÿ åôåêòèâíèìè õàð÷îâèìè äîáàâêàìè ïåðåäáà÷ຠïîãëèáëåíå âèâ÷åííÿ óñ³õ ¿õí³õ ñêëàäîâèõ ç ìåòîþ çàïîá³ãàííÿ ¿õíüîãî íåãàòèâíîãî âïëèâó íà çäîðîâ’ÿ íàñåëåííÿ.
Ìåòà ðîáîòè – óçàãàëüíèòè â³äîì³ â ë³òåðàòóð³ äàí³ ïðî õ³ì³÷íèé ñêëàä ðîñëèííî¿ ñèðîâèíè òà íàóêîâ³ äàí³ ïðî ¿õíþ á³îëîã³÷íó àêòèâí³ñòü ³ ìåòîäè ¿õíüîãî àíàë³òè÷íîãî âèÿâëåííÿ.
Óí³êàëüí³ ôàðìàêîëîã³÷í³ âëàñòèâîñò³ õàð÷îâèõ äîáàâîê íà îñíîâ³ ë³êàðñüêèõ ðîñëèíí îáóìîâëåí³ êîìïëåêñíèì õàðàêòåðîì 䳿 á³îëîã÷íî àêòèâíèõ ñïîëóê, ÿê³ º â ñêëàä³ ÿê ïåðâèííèèõ (ñàõàðà, îë³ãî- òà ïîë³ñàõàðèäè, îðãàí³÷í³ ³ ì³íåðàëüí³ êèñëîòè, ë³ï³äè, ë³ïî¿äè, â³òàì³íè, ôåðìåíòè, ì³íåðàëüí³ ðå÷îâèíè) òàê ³ âòîðèííèõ ìåòàáîë³ò³â (ñòåðî¿äè - ô³òîñòåðèíè, êàðä³îñòåðî¿äè, ñòåðî¿äí³ ñàïîãåí³íè), (òåðïåíî¿äè - ³ðèäî¿äè, êîìïîíåíòè åô³ðíèõ ìàñåë, ñìîëè, òðèòåðïåíî¿äè, êàðîòèíî¿äè, êàó÷óê), (ôåíîëüí³ ñïîëóêè - ïðîñò³ ôåíîëè ³ ¿õí³ ïîõ³äí³, ïîõ³äí³ àíòðàöåíó, äóáèëüí³ ðå÷îâèíè) òà àëêàëî¿ä³â.
Êîìïëåêñ öèõ ñïîëóê ïðîÿâëÿº ôîòîñåíñèá³ë³çóþ÷ó,ñïàçìîë³òè÷íó òà íåôðîë³òè÷íó àêòèâí³ñòü, àíòèêîàãóëþþ÷ó, àíòèì³êðîáíó, åñòðîãåííó, ïðîòèïóõëèííó, ïðîòèòóáåðêóëüîçíó òà àíàëãåòè÷íó ³ ñåäàòèâíó ä³þ, âïëèâຠíà àíòèäåïðåñèâíèé åôåêò.
Äëÿ ¿õíüîãî âèÿâëåííÿ â ë³êàðñüê³é ñèðîâèí³ òà õàð÷îâèõ äîáàâêàõ ðîçðîáëåí³ òà âèêîðèñòîâóþòüñÿ ÿê êëàñè÷í³ ðåàêö³¿ (ðåàêòèâè Ìîë³øà, Ôåë³íãà, ðåàêö³ÿ ³ëüñîíà ÷èñëî îìèëåííÿ, åô³ðíå òà éîäíå ÷èñëà, ëàêòîííà ïðîáà, òèòðèìåòð³ÿ) òàê ³ ô³çèêî-õ³ì³÷í³ ìåòîäè (ôëóîðåñö³ÿ â ÓÔ-ñâ³òë³, ïîëÿðîãðàô³ÿ, ñïåêòðîôîòîìåòð³ÿ, õðîìàòî-ìàñ-ñïåêòðîìåòð³ÿ)
Ìåòà ðîáîòè – óçàãàëüíèòè â³äîì³ â ë³òåðàòóð³ äàí³ ïðî õ³ì³÷íèé ñêëàä ðîñëèííî¿ ñèðîâèíè òà íàóêîâ³ äàí³ ïðî ¿õíþ á³îëîã³÷íó àêòèâí³ñòü ³ ìåòîäè ¿õíüîãî àíàë³òè÷íîãî âèÿâëåííÿ.
Óí³êàëüí³ ôàðìàêîëîã³÷í³ âëàñòèâîñò³ õàð÷îâèõ äîáàâîê íà îñíîâ³ ë³êàðñüêèõ ðîñëèíí îáóìîâëåí³ êîìïëåêñíèì õàðàêòåðîì 䳿 á³îëîã÷íî àêòèâíèõ ñïîëóê, ÿê³ º â ñêëàä³ ÿê ïåðâèííèèõ (ñàõàðà, îë³ãî- òà ïîë³ñàõàðèäè, îðãàí³÷í³ ³ ì³íåðàëüí³ êèñëîòè, ë³ï³äè, ë³ïî¿äè, â³òàì³íè, ôåðìåíòè, ì³íåðàëüí³ ðå÷îâèíè) òàê ³ âòîðèííèõ ìåòàáîë³ò³â (ñòåðî¿äè - ô³òîñòåðèíè, êàðä³îñòåðî¿äè, ñòåðî¿äí³ ñàïîãåí³íè), (òåðïåíî¿äè - ³ðèäî¿äè, êîìïîíåíòè åô³ðíèõ ìàñåë, ñìîëè, òðèòåðïåíî¿äè, êàðîòèíî¿äè, êàó÷óê), (ôåíîëüí³ ñïîëóêè - ïðîñò³ ôåíîëè ³ ¿õí³ ïîõ³äí³, ïîõ³äí³ àíòðàöåíó, äóáèëüí³ ðå÷îâèíè) òà àëêàëî¿ä³â.
Êîìïëåêñ öèõ ñïîëóê ïðîÿâëÿº ôîòîñåíñèá³ë³çóþ÷ó,ñïàçìîë³òè÷íó òà íåôðîë³òè÷íó àêòèâí³ñòü, àíòèêîàãóëþþ÷ó, àíòèì³êðîáíó, åñòðîãåííó, ïðîòèïóõëèííó, ïðîòèòóáåðêóëüîçíó òà àíàëãåòè÷íó ³ ñåäàòèâíó ä³þ, âïëèâຠíà àíòèäåïðåñèâíèé åôåêò.
Äëÿ ¿õíüîãî âèÿâëåííÿ â ë³êàðñüê³é ñèðîâèí³ òà õàð÷îâèõ äîáàâêàõ ðîçðîáëåí³ òà âèêîðèñòîâóþòüñÿ ÿê êëàñè÷í³ ðåàêö³¿ (ðåàêòèâè Ìîë³øà, Ôåë³íãà, ðåàêö³ÿ ³ëüñîíà ÷èñëî îìèëåííÿ, åô³ðíå òà éîäíå ÷èñëà, ëàêòîííà ïðîáà, òèòðèìåòð³ÿ) òàê ³ ô³çèêî-õ³ì³÷í³ ìåòîäè (ôëóîðåñö³ÿ â ÓÔ-ñâ³òë³, ïîëÿðîãðàô³ÿ, ñïåêòðîôîòîìåòð³ÿ, õðîìàòî-ìàñ-ñïåêòðîìåòð³ÿ)
ÊËÞ×β ÑËÎÂÀ:
Õàð÷îâ³ äîáàâêè, ë³êàðñüê³ ðîñëèíè, á³îëîã³÷íî àêòèâí³ ñïîëóêè, á³îëîã³÷íà àêòèâí³ñòü, ìåòîäè àíàë³çó.
˲ÒÅÐÀÒÓÐÀ:
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ÄËß ÖÈÒÓÂÀÍÍß:
Ëÿøåíêî Â.²., Ãîë³÷åíêîâ Î.Ì., Îñòàí³íà Í.Â., Êóçíåöîâà Î.Ì., Ëåâ³í Ì.Ã., Áðÿçêàëî Â.Â., Ìàéñòðåíêî Ç.Þ. Á³îëîã³÷íî àêòèâí³ ñïîëóêè ë³êàðñüêèõ ðîñëèí – ÿê áàçîâà ñêëàäîâà õàð÷îâèõ äîáàâîê. Íàóêîâèé àíàë³ç. ó㳺íà íàñåëåíèõ ì³ñöü : çá. íàóê. ïð. Ê., 2022. Âèï. 72. Ñ. 124-135.