ó㳺íà íàñåëåíèõ ì³ñöüISSN: 2707-0441 eISSN: 2707-045X
Âèïóñê 75, 2025   -   Ñòîð³íêè: 34-47
ղ̲×Ͳ ÒÀ ̲ÊÐÎÁ²ÎËÎò×Ͳ ÀÑÏÅÊÒÈ ÇÍÅÇÀÐÀÆÅÍÍß ÂÎÄÈ Ä²ÎÊÑÈÄÎÌ ÕËÎÐÎÌ
Ìî곺íêî À.Â.1
1 Íàö³îíàëüíèé óí³âåðñèòåò «Îñòðîçüêà àêàäåì³ÿ»

ÓÄÊ: 546.134:628.16
https://doi.org/10.32402/hygiene2025.75.034

ÀÍÎÒÀÖ²ß:
Ìåòà. Àíàë³ç õ³ì³÷íèõ òà ì³êðîá³îëîã³÷íèõ àñïåêò³â çíåçàðàæåííÿ âîäè ä³îêñèäîì õëîðîì.
Îá’ºêò ³ ìåòîäè äîñë³äæåííÿ. Îá’ºêò: ä³îêñèä õëîðó. Ìåòîäè äîñë³äæåííÿ: á³áë³îìåòðè÷í³, àíàë³òè÷í³. Ïðîâåäåíî óçàãàëüíåííÿ òà àíàë³ç äàíèõ ë³òåðàòóðè ùîäî õ³ì³÷íèõ òà ì³êðîá³îëîã³÷íèõ àñïåêò³â âèâ÷åííÿ ä³îêñèäó õëîðó ÿê çàñîáó çíåçàðàæåííÿ âîäè.
Ðåçóëüòàòè äîñë³äæåííÿ òà ¿õ îáãîâîðåííÿ. Ñôîðìóëüîâàíî îäíîñòàéíó äóìêó ïðîâ³äíèõ äîñë³äíèê³â ä³îêñèäó õëîðó ÿê äåç³íôåêòàíòó: íåçâàæàþ÷è íà âèêîðèñòàííÿ íàäñó÷àñíèõ ìåòîä³â äîñë³äæåíü ³ åêñïîíåíö³àëüíèé ð³ñò ïóáë³êàö³é, ä³îêñèä õëîðó º íàéìåíø âèâ÷åíèì ðåàãåíòîì. Ïðåäñòàâëåíî äîêëàäíèé àíàë³ç ôóíäàìåíòàëüíî¿ õ³ì³êî-á³îëîã³÷íî¿ ïàðàäèãìè ùîäî óòâîðåííÿ ³ ó÷àñò³ â³ëüíîãî àêòèâíîãî õëîðó ÿê âòîðèííîãî îêèñíþâà÷à ï³ä ÷àñ äåç³íôåêö³¿ ä³îêñèäîì õëîðó: ä³îêñèä õëîðó ãîëîâíèì ÷èíîì â³äïîâ³äຠçà ïîøêîäæåííÿ ìåìáðàíè, çàâäÿêè ÷îìó óòâîðåíèé â³ëüíèé àêòèâíèé õëîð ÿê âòîðèííèé îêèñíþâà÷ âèêëèêຠïîøêîäæåííÿ öèòîïëàçìè. Ïîêàçàíî, ùî ä³îêñèä õëîðó ìຠð³çí³ ìåõàí³çìè ³íàêòèâàö³¿ ð³çíèõ âèä³â ì³êðîîðãàí³çì³â, çâàæàþ÷è íà ¿õ ð³çíó ñòðóêòóðíó ìîðôîëîã³þ, êë³òèííèé ñêëàä, îá’ºì ³ ðåçèñòåíòí³ñòü. Äëÿ áàêòåð³é ³ ãðèá³â ëåòàëüíîþ ì³øåííþ ä³îêñèäó õëîðó º ðóéíóâàííÿ ñòðóêòóðè êë³òèííî¿ ìåìáðàíè, çì³íà ïðîíèêíîñò³ âíóòð³øíüîêë³òèííèõ ðå÷îâèí, ïîøêîäæåííÿ ïåðåêèñíîãî îêèñëåííÿ ë³ï³ä³â ³ ãåíåòè÷íîãî ìàòåð³àëó. Ëåòàëüíîþ ìåòîþ ä³îêñèäó õëîðó äëÿ â³ðóñ³â º äåñòðóêö³ÿ â³ðóñíîãî á³ëêà êàïñèäó òà äåôðàãìåíòàö³ÿ ÐÍÊ àáî ÄÍÊ. Âñòàíîâëåíî, ùî ð³âí³ ³íàêòèâàö³¿ íàéïðîñò³øèõ (Cryptosporidium parvum oocyst, öèñò Nagleria gruberi) ä³îêñèäîì õëîðó òà îçîíîì ìàéæå ³äåíòè÷í³. Ïîêàçàíî, ùî ãîëîâíèé ìåõàí³çì ³íàêòèâàö³¿ ä³îêñèäîì õëîðó áàêòåð³àëüíèõ ñïîð ïîëÿãຠó ïîøêîäæåíí³ âíóòð³øíüî¿ ìåìáðàíè ñïîðè. Âèÿâëåíî, ùî àëüãàöèäíà ä³ÿ ä³îêñèäó õëîðó ïîëÿãຠó âïëèâ³ ³ íà ñòðóêòóðè çàõèñíîãî ïîêðèòòÿ êë³òèíè, ³ íà âíóòð³øíüîêë³òèíí³ êîìïîíåíòè. Óçàãàëüíåíî ðåçóëüòàòè äîñë³äæåíü âïëèâó ä³îêñèäó õëîðó ³ õëîðèòó (ÿê ïîá³÷íîãî ïðîäóêòó) íà á³îïë³âêè. Îáãðóíòîâàíî íåîáõ³äí³ñòü çàáåçïå÷åííÿ çàëèøêîâî¿ êîíöåíòðàö³¿ ä³îêñèäó õëîðó ó ïèòí³é âîä³ ç âîäîðîçïîä³ëüíèõ ñèñòåì.
Âèñíîâîê. Âèçíàíî ñïðàâåäëèâîþ îäíîñòàéí³ñòü äóìîê ð³çíèõ àâòîð³â ùîäî íåîáõ³äíîñò³ ïîäàëüøèõ äîñë³äæåíü äëÿ ïîâíîãî ðîçóì³ííÿ ìåõàí³çì³â ³íàêòèâàö³¿ ä³îêñèäîì õëîðó ïàòîãåí³â òà òîêñèí³â.

ÊËÞ×β ÑËÎÂÀ:
ijîêñèä õëîðó, âîäà, õ³ì³÷í³ ðåàêö³¿, ³íàêòèâàö³ÿ, áàêòåð³¿, â³ðóñè, íàéïðîñò³ø³, ñïîðè, ãðèáè, ì³êðîâîäîðîñò³, á³îïë³âêè.

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