Hygiene of populated placesISSN: 2707-0441 eISSN: 2707-045X
Issue 75, 2025   -   Pages: 99-107
THE ROLE OF NUTRITION IN THE PREVENTION OF ARTERIAL HYPERTENSION AS A COMPONENT OF METABOLIC SYNDROME (based on the analysis of the PURE study and own observations)
O.Yu. Mykhailenko1
1 SI "Marzieiev Institute for Public Health of the NAMS of Ukraine"
https://doi.org/10.32402/hygiene2025.75.099

SUMMÀRY:
Purpose. To assess the features of the development of arterial hypertension in people with metabolic syndrome and to substantiate the principles of nutrition for prevention.
Object and research methods. 432 adult patients aged 20 to 69 years were examined, including 349 women and 83 men. The survey was conducted among respondents using a questionnaire. General clinical indicators were recorded: determination of height, weight with subsequent calculation of body mass index (kg/m2), systolic (SAT) and diastolic (DAT) blood pressure. Among the laboratory indicators, the following attracted attention: total cholesterol (Total C), glucose, insulin resistance marker (Homa-IR index). Statistical processing was carried out using correlation analysis. The topic of the article is covered in graphs, tables and diagrams. During the study, the principles of bioethics were observed, as well as the provisions of the Order of the Ministry of Health “On Approval of the Procedure for Conducting Clinical Trials” and the Model Regulation on the Ethics Commission No. 66 dated February 13, 2006. All patients signed an informed consent to participate in the study.
Research results and their discussion. A registry of respondents – men and women – who were under the influence of a modified factor – overweight or obesity, which is a trigger for the spread of conditions such as arterial hypertension, hypercholesterolemia, and hyperglycemia was created. The study found that 85% of respondents had some degree of obesity or overweight. A significant relationship between quantitative indicators was also confirmed using Pearson's correlation analysis (r) between the parameters of SBP and DBP (r=0.9608, p≤0.01), BMI (r=0.75664, p≤0.05), Total Xc (r=0.69983, p≤0.05), glucose (r=0.73268, p≤0.05); between BMI and Total Xc (r=0.7139, p≤0.05), and glucose (r=0.63816, p≤0.05). This once again confirms that systolic blood pressure increases simultaneously with diastolic blood pressure, and blood pressure depends on the increase in glucose, cholesterol, and BMI levels, because these parameters affect the condition of blood vessels and the heart.
Conclusions. An in-depth, comprehensive examination with simultaneous determination of anthropometric, hemodynamic, and hormonal indicators of health status allowed us to substantiate the role of nutrition in the prevention of arterial hypertension in patients with metabolic syndrome. It was shown that 85% of respondents had varying degrees of obesity or overweight, which can be considered a risk factor for the development of arterial hypertension. A significant relationship between quantitative indicators was established using Pearson's correlation analysis (r) between pressure and total cholesterol, glucose, and body mass index. It is highlighted that rational changes in eating habits are a simple, affordable, and effective path to a healthy heart and longevity.
Preventive actions. In order to prevent the occurrence of arterial hypertension, it is recommended that men and women implement nutritional principles.

KEYWORDS:
Arterial hypertension, metabolic syndrome, body mass index, blood pressure, nutrition.

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FOR CITATION:
Mykhailenko OYu. [The role of nutrition in the prevention of arterial hypertension as a component of metabolic syndrome (based on the analysis of the PURE study and own observations)]. Hygiene of Populated Places. 2025;75:99-107. Ukrainian. doi: https://doi.org/10.32402/hygiene2025.75.099