Hygiene of populated placesISSN: 2707-0441 eISSN: 2707-045X
Issue 69, 2019   -   Pages: 88-95
IDENTIFICATION OF NON-CARCINOGENIC RISKS FROM ORAL INTAKE OF PRIORITY CHEMICALS IN THE ORGANISM
I.O. Chernichenko1, V.F. Babii1, O.M. Litvichenko1, O.Ye. Kondratenko1, N.V. Balenko1, D.O. Hlavachek1
1 STATE INSTITUTION O.M. MARZIEIEV INSTITUTE FOR PUBLIC HEALTH NAMSU

: 614.7:576.385.5:616-084
https://doi.org/10.32402/hygiene2019.69.088

SUMMRY:
Objective: We studied the state of the pollution of drinking water, foodstuffs (animal and plant origin) with the carcinogenic compounds.
Materials and methods: The prior carcinogens of three classes were selected as indicator substances: polycyclic aromatic hydrocarbons, nitrosamines and heavy metals. Investigations were conducted at the territory of one region Kyiv and Kyiv oblast.
Results: The results of the presence of prior chemical carcinogens in the main foodstuffs of the population are considered in this article. The total doses of carcinogens, entering into the organism with a food intake, were calculated. The critical organs and systems they affect were established. Ni-trosamines and heavy metals are shown to be the most dangerous by the indicator of non-carcinogenic risk, and liver and gastrointestinal tract are the most sensitive to their impact.
Conclusions: Domestic hygienic standards do not guarantee a safety of domestic products and drinking water for a human. These standards require a revision of the methodological approaches to the assessment of foodstuffs and their unification in accordance with the international norms and standards.

KEYWORDS:
non-carcinogenic risk, chemical pollution, foodstuffs.

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FOR CITATION:
Chernichenko I.O., Babii V.F., Litvichenko O.M., Kondratenko O.Ye., Balenko N.V., Hlavachek D.O. Vyznachennia nekantserohennykh ryzykiv vid peroralnoho nadkhodzhennia priorytetnykh khimichnykh rechovyn v orhanizm [Identification of non-carcinogenic risks from oral intake of priority chemicals in the organism]. In : Hihiiena naselenykh mists : zb. nauk. pr. [Hygiene of Populated Places]. Kyiv ; 2019 ; 69 : 88-95 (in Ukrainian).