| Hygiene of populated places | ISSN: 2707-0441 eISSN: 2707-045X |
Issue 64, 2014 - Pages: 318-322
THE EXPERIMENTAL STUDING OF THE INFLUENCE OF NITRATE, NITRITE AND LEAD ON CNS FUNCTIONAL STATE
V.I. Fedorenko1, L.M. Kitsula1
1 DANYLO HALYTSKY LVIV NATIONAL MEDICAL UNIVERSITY
ÓÄÊ: 613.8:(546.173+546.175+546.815):616.831
SUMMÀRY:
The dynamics of single and joint action of nitrates, nitrites and lead in doses of 1/10 LD50 and 1/100 LD50 on ÒLI (total-limited index) and behavioral reactions of white rats in under-acute experiment were studied.
The changes in behavioural reactions (latency period, vertical and horizontal activity) have an unidirectional character in single action of all components and their joint action, – in particular activity is suppressed by 2-4 times, depending on the substance, dose, and observation days. The mink reflex in animals has reduced under the influence of a binary mixture at 1 /10 LD50 and under the influence of the lead and the ternary mixture regardless of the dose.
The changes in behavioural reactions (latency period, vertical and horizontal activity) have an unidirectional character in single action of all components and their joint action, – in particular activity is suppressed by 2-4 times, depending on the substance, dose, and observation days. The mink reflex in animals has reduced under the influence of a binary mixture at 1 /10 LD50 and under the influence of the lead and the ternary mixture regardless of the dose.