Hygiene of populated placesISSN: 2707-0441 eISSN: 2707-045X
Issue 69, 2019   -   Pages: 139-146
STUDY OF THE EFFECT OF ELECTROMAGNETIC RADIATION ON THE STATE OF PRO- AND ANTIOXIDANT PROCESSES IN THE BLOOD OF EXPERIMENTAL ANIMALS
L.A. Tomashevska1, T.E. Kravchun1, N.V. Didyk1
1 STATE INSTITUTION O.M. MARZIEIEV INSTITUTE FOR PUBLIC HEALTH NAMSU

: 613.648.2:577. 152.1
https://doi.org/10.32402/hygiene2019.69.139

SUMMRY:
The aim of the work was to determine in the experiment the effect of EMR with different inten-sity and differentiated by time of exposure.
Subject and methods. The effect of EMR on the pro- and antioxidant processes in the organ-ism. Biochemical, statistical methods.
Results and dicussions. The investigations were conducted under conditions of the 4-month chronic experiment on outbred white rats which were divided into groups according to the EMR cur-rent intensity of 2000 V/m×min., 4000 V/m×min., 6000 V/m×min.
The findings allow us to make a conclusion that in animals exposed to electromagnetic radia-tion, metabolic processes of antioxidant balance are disturbed, which is confirmed by the changes in ceruloplasmin levels and catalase activity in animal blood plasma. The investigations demonstrated that effect of EMR occurs through the activation of lipid peroxidation, the distribution and mobiliza-tion of antioxidant protection systems, the development of compensatory-adaptive mechanisms for a stable state of the functioning of organism systems.
Conclusions. In revealing of the injuries of the functional systems, the indicators of biochemi-cal processes of oxidation-reduction, which slow down or accelerate, the forming response of the or-ganism to the effect of EMR, are of great importance.
There is an imbalance in the system "lipid peroxidation-antioxidant system" (POL-AOS), which indicates the peroxide nature of the disorders in the organism under effect of EMR.
Thus, the investigations have shown the impact of the EMR occurs through the activation of lipid peroxidation, the distribution and mobilization of antioxidant protection systems, the develop-ment of compensatory-adaptive mechanisms for a stable state of organism functioning.

KEYWORDS:
lipid peroxidation, electromagnetic radiation, oxidative stress, hematological indicators.

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FOR CITATION:
Tomashevska L.A., Kravchun T.E., Didyk N.V. Doslidzhennia vplyvu elektromahnitnykh vyprominiuvan na stan pro- ta antyoksydantnykh protsesiv v krovi piddoslidnykh tvaryn [Study of the effect of electromagnetic radiation on the state of pro- and antioxidant processes in the blood of experimental animals]. In : Hihiiena naselenykh mists : zb. nauk. pr. [Hygiene of Populated Places]. Kyiv ; 2019 ; 69 : 139-146 (in Ukrainian).