Hygiene of populated placesISSN: 2707-0441 eISSN: 2707-045X
Issue 72, 2022   -   Pages: 95-100
THE CHARACTER OF CHANGES IN INDIVIDUAL BIOCHEMICAL INDICATORS UNDER THE CONDITIONS OF THE COMBINED EFFECT OF ELECTROMAGNETIC FIELD 50 Hz AND NITROSAMINE ON THE ORGANISMS OF RESEARCH ANIMALS
L.A. Tomashevskaya1, V.S. Tstsruk1, T.E. Kravchun1, N.V. Diduk1
1 STATE INSTITUTION O.M. MARZIEIEV INSTITUTE FOR PUBLIC HEALTH NAMSU

: 614.718:613.648.2
https://doi.org/10.32402/hygiene2022.72.095

SUMMRY:
Objective. Advancement of the effects of electromagnetic radiation and endogenous nitrosamines (a combination of tetracycline and sodium nitrate) on the biochemical parameters of the blood of experimental rats.
Materials and methods. Combined effect of electromagnetic radiation and combination of tetracycline with sodium nitrate on the biochemical parameters.
Results. As a result of the chronic experiment, the obtained results showed that the influence of the studied factors on the body of experimental animals can cause a violation of the indicators of metabolic processes. Such a tendency to imbalance indicators can be a kind of indicator of metabolic compensatory changes in the body under the influence of electromagnetic radiation and chemicals, depending on the duration of action. The presence of time dependence was observed with the isolated effect of the factors, but the most pronounced changes in biochemical indicators were observed under the conditions of the combined effect of the factors, which may be important for the prediction of the harmfulness of the long-term effects of the studied substances on the functional state.
Conclusions. Biochemical studies revealed functional changes in the metabolic systems of homeostasis. It was established that the nature and severity of the effects depended on the active factors and the combination of these factors. Also, the time of the factor's action plays an important role in this experiment, since the most pronounced and significant changes in the studied parameters were manifested only after 120 days (4 months) of exposure.

KEYWORDS:
Electromagnetic radiation, sodium nitrate, tetracycline, nitrosamines, combined action, biochemical indicators, total protein, bilirubin, creatinine.

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FOR CITATION:
Tomashevskaya LA, Tstsruk VS, Kravchun TE, Diduk NV. The character of changes in individual biochemical indicators under the conditions of the combined effect of electromagnetic field 50 Hz and nitrosamine on the organisms of research animals. Hygiene of populated places. 2022;72:95-100. Ukrainian.