Hygiene of populated placesISSN: 2707-0441 eISSN: 2707-045X
Issue 64, 2014   -   Pages: 142-151
ADAPTAION A RESPONSE OF AN ORGANISM AT A LEVEL OF A CYCLE THREECARBONIC OF ACIDS FOR WANT OF INGALATION BY PRODUCTS OF BURNING POLYMERIC OF MATERIALS
V.. Lyshenko1, .. Golichenkov1, .. Voloshenko1, .U. Kucherenko1, G.P. Umanec1
1 STATE INSTITUTION O.M. MARZIEIEV INSTITUTE OF HYGIENE AND MEDICAL ECOLOGY NAMSU

SUMMRY:
For want of acute ingalation an organism produkts of burning polyvinylchloride and farbens of mate-rials the mechanism formations of an adaptive response per the first day after ingalation of period is directed on removal hiperredactions of a circuit of transfer of electrons by normalization of a parity
NAD +/ NAD. at the expense of switching pyruvat on oxidation cytosolic NAD. up to NAD+, that show to increase of concentration lactat and decrease pyruvatt in time.
In an adaptive response sukcynat is lider a link in a circuit of transfer of electrons (CTE), to what the sharp magnification it of concentration in importrat a moment after ingalation and further heavily decrease to a level of monitoring testifies. Activation of synthesis glutamat and sharp decrease of concentration α-ketoglutarat testifies to mobilization transamiyazions "glutamat-ketoglutarats" re-sponses, which is directed on restoring of fund sukcynat in CTA, which also is supported at the ex-pense of return responses "malat-fumarat-sukcynat".
Owing to accumulation reductionsof the forms coferments NAD. that FAD.H2 for want of defect of cell-like oxygen there are conditions for collateral loss of electrons from CTE and them of interaction from oxygen, that results to do not controlation to formation active it of the forms oxygen and development of oxidation lipids.