Hygiene of populated placesISSN: 2707-0441 eISSN: 2707-045X
Issue 67, 2017   -   Pages: 220-228
DOWN'S SYNDROME AND THE SEX RATIO IN NEWBORNS (review of literature with own research)
L. Pedan1, V. Galagan2, E. Omelchenko1, G. Kachko1, O. Polka1, O. Timchenko1
1 STATE INSTITUTION O.M. MARZIEIEV INSTITUTE FOR PUBLIC HEALTH NAMSU
2 NATIONAL CHILDREN'S SPECIALIZED HOSPITAL "OHMATDIT" OF THE MINISTRY OF HEALTH OF UKRAINE
https://doi.org/10.32402/hygiene2017.67.220

SUMMRY:
A study of various factors that affect the sex ratio in children with Down's syndrome is dis-cussed by many authors.
The spectrum of chromosome aberrations in the Down's syndrome includes regular trisomy (more than 90% of all cases), translocation variants (4.0-6.8%) and mosaics (2.2% on average). Regular trisomy constitutes a larger number of cases. Its determines the characteristic prevalence of males among the sick individuals.
As a result of the analysis, it was found that boys were born more than girls, the sex ratio was 1.00 to 1.50. In general, the gender ratio is more than 1.00, indicating prevalence of boys over girls in Down's syndrome.
Women at the age of 30 and older have a highest opportunity (70.83%) to give birth to a child with Down's syndrome.

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