| Hygiene of populated places | ISSN: 2707-0441 eISSN: 2707-045X |
Issue 67, 2017 - Pages: 267-273
TO THE QUESTION OF APPLICATION OF THE CYTOCHEMICAL METHOD OF DETERMINING THE REACTIVITY OF NEUTROPHILES IN THE RATS BLOOD
L.A. Tomashevskaya1, L.V. Bogdanovich1, T.E. Kravchun1
1 STATE INSTITUTION “O.M. MARZIEIEV INSTITUTE FOR PUBLIC HEALTH” NAMSU
SUMMÀRY:
In the study of the bioeffects of the environment, the main material is blood. Blood cells carry information about the physiological state of the body.
Experimental determination of reactivity of neutrophils and erythrocyte membranes with the help of cytochemical tests makes it possible to establish the direction of functional changes in the or-ganism of animals when forming adaptive or stressful processes to the influence of factors of the ex-ternal and internal environment.
The study of the state of blood cell membranes, as an indicator of negative reactions of the body, is a promising direction in determining health risk criteria in the face of environmental factors.
Experimental determination of reactivity of neutrophils and erythrocyte membranes with the help of cytochemical tests makes it possible to establish the direction of functional changes in the or-ganism of animals when forming adaptive or stressful processes to the influence of factors of the ex-ternal and internal environment.
The study of the state of blood cell membranes, as an indicator of negative reactions of the body, is a promising direction in determining health risk criteria in the face of environmental factors.
REFERENCES:
1. Bogdanovych L.V. Funktsionalnyi stan peryferychnoi krovi shchuriv pry obmezhenni yikh fizychnoi aktyvnosti [Functional State of the Peripheral Blood of Rats While Limiting Their Physical Activity]. In : Problemy, dostizheniya i perspektivy razvitiya mediko-biologicheskikh nauk i prakticheskogo zdravookhraneniya: trudy Krymskogo GMU im. SI Georgiyevskogo [Problems, Achievements and Prospects for the Development of Biomedical Sciences and Practical Health Care: Proc. of the Crimean State S.I. Georgievsky Medical University]. Simferopol ; 2004 ; 140 : 6-8 (in Ukrainian).
2. Kravchun Ò.Ye. Tsytolohichna kharakterystyka klityn krovi ta kistkovoho mozku tvaryn pry korotkostrokovii dii elektromahnitnoho vyprominiuvannia [Cytological Characteristic of Blood Cells and Bone Marrow of the Animals in the Short-Term Action of Electromagnetic Radiation]. In : Hihiiena naselenykh mists : zb. nauk. pr. [Hygiene of Populated Places: Sci. Works Coll.]. Kyiv ; 2011 ; 58 ; 241-245 (in Ukrainian).
3. Tomashevska L.A., Kravchun T.Ye., Didyk N.V., Kazemir V.S. and Lemeshko L.P. Eksperymentalna otsinka vplyvu khloroformu, shcho nadkhodyt do orhanizmu z pytnoiu vodoiu [Experimental Evaluation of the Effects of Chloroform Entering into the Organism with Drinking Water]. In : Aktualni pytannia hihiieny ta ekolohichnoi bezpeky Ukrainy (odynadtsiati marzieievski chytannia) : zb. tez dop. naukovo-prakt. konf. [Topical Issues of Hygiene and Environmental Safety of Ukraine (the Eleventh Marzieiev’s Reading): Coll. Abs.Sci-Pract. Conf.]. Kyiv ; 2015 ; 15 : 273-275 (in Ukrainian).
4. Tomashevska L.A. and Kravchun T.Ye. Dovkillia ta zdorovia (Environment and Health). 2012 : 3 (62) : 10-13 (in Ukrainian). DOI : https://doi.org/10.5339/qproc.2012.mutagens.3.13
5. Ivanova E. and Ivanov B. Experimental Ðathology and Ðarasitology. 2000 ; 4 : 42-47.
6. Kravchun T.Ye. Vplyv elektromahnitnoho vyprominiuvannia riznykh rivniv navantazhennia na klityny krovi. [Effect of Electromagnetic Radiation of Different Levels of Load on Blood Cells]. In : Hihiiena naselenykh mists : zb. nauk. pr. [Hygiene of Populated Places: Sci. Works Coll.]. Kyiv ; 2007 ; 49 : 251-255 (in Ukrainian).
7. Tomashevska L.A., Obukhan K.I. and Kravchun T.Ye. Dovkillia ta zdorovia (Environment and Health). 2009 ; 2 (49) : 9-13 (in Ukrainian).
8. Park B.H. J. Pediatr. 1971 ; 78 : 376-378. DOI : https://doi.org/10.1016/S0022-3476(71)80048-3
9. Artyukhov V.G., Ryazantseva L.T. and Basharina O.V. Tsitologiya. 2001 ; 43 (4) (in Russian).
10. Djaldetti M., Salman H. and Bergman M. Microsc Res Tech. 2002 ; 57 (6) : 421-431. DOI : https://doi.org/10.1002/jemt.10096